linalool

Linalool has the ability to induce apoptosis in cancer cell lines such as U87-MG, HepG-2, and SW620 through oxidative stress. In animal experiments, Linalool significantly reduced tumor growth in S-180 solid tumor mouse models.

Antibacterial Effects:
Linalool exerts antibacterial effects by disrupting cellular membranes.

Anti-inflammatory Effects:
Linalool has significant anti-inflammatory properties by inhibiting NF-κB, which reduces inflammatory responses.

Neuroprotective Effects:
As a competitive NMDA receptor antagonist, Linalool exhibits neuroprotective effects by alleviating oxidative stress and mitochondrial dysfunction caused by glutamate and NMDA toxicity.

Antianxiety and Antidepressant Effects:
Linalool also demonstrates antianxiety and antidepressant activities, positively impacting the nervous system.

Cardiac, Liver, Kidney, and Lung Protection:
Linalool exhibits anti-cardiotoxic effects and protects the liver from damage by activating Nrf2 to induce antioxidant defenses. Additionally, it provides protection to the kidneys and lungs.

Other Effects

Analgesic Effects:
Linalool has shown analgesic effects in animal experiments, with mechanisms potentially related to the TRPA1-independent pathway.

Metabolic Regulation:
Linalool is a PPARα ligand that can reduce plasma thyroglobulin (TG) levels and alter liver transcriptome structure and plasma metabolites.

Modifying Plant Aroma:
In plants, Linalool is a product synthesized by linalool synthase (LIS) catalysis. Research on the cloning, prokaryotic expression, and transgenic modification of LIS genes can help change plant aroma and enhance plant insect resistance.

This translation accurately conveys the original meaning while maintaining the scientific and technical accuracy of the terms used.